金丹
发布时间2023-06-07 14:56:58     作者:    浏览次数: 次

金丹,女,汉族,2007年毕业于四川大学,博士,副研究员,耶鲁大学访问学者,硕士生导师。主要从事昆虫病原真菌响应逆境胁迫及致病的相关机制研究。主持国家自然科学基金、教育部新教师基金、重庆市自然科学基金、教育部基本科研业务费专项基金等项目。发表学术论文20余篇;申请发明专利多项。


联系方式

Email: jindancj@swu.edu.cn          

主持课题

1、国家自然科学基金面上项目:天冬氨酸蛋白酶BbASP介导细胞壁改变调节球孢白僵菌逆境适应及毒力的分子机制(32270130

2、国家自然科学基金:噻唑合成酶BbThI在球孢白僵菌紫外辐射损伤耐受中的作用和机制(30800026

3、教育部新教师基金:噻唑合成酶BbThI在球孢白僵菌紫外辐射耐受中的作用和机制(200806351027

4、重庆市自然科学基金项目泛素降解途径底物结合蛋白BbGrrA基因影响球孢白僵菌毒力的机制研究cstc2019jcyj-msxmX0413

5、重庆市自然科学基金:利用球孢白僵菌homeobox基因构建高毒力生物杀虫剂的研究 (CSTC2015JCYJA0824)

6、重庆市自然科学基金:应用球孢白僵菌噻唑合成酶基因培育高产VB1番茄果实(CSTC,2008BB1264

7、基本科研业务费重点项目:“GroupIII组氨酸激酶BbMHK1F-box蛋白互作在球孢白僵菌高温耐受中的调控机制研究XDJK2020B041

8、基本科研业务费专项项目(重点项目):球孢白僵菌光裂合酶基因功能及利用该基因构建高UV耐受菌株的研究(XDJK2013B033

 已发表论文

1. Dan Jin; Binda Sun; Wenqi Zhao; Jincheng Ma;Qiuyue Zhou; Xuemeng Han; Yalin Mei; Yanhua Fan; Yan Pei. Thiamine-biosynthesis genes Bbpyr and Bbthi are required for conidial production a nd cell wall integrity of the entomopathogenic fungus Beauveria bassiana. Journal of invertebrate pathology. 2021, 184: 107639-107649

2.  Dan Jin, Min Wu, Bosheng Li, Birte Bücker, Philipp Keil, Shaoman Zhang, Jigang Li, Dingming Kang, Jie Liu, Jie Dong, Xing Wang Deng, Vivian Irish, Ning Wei. The COP9 Signalosome regulates seed germination by facilitating protein degradation of RGL2 and ABI5. PLoS Genet, 2018, 14(2): e1007237.

3.  Dan Jin, Bosheng Li, Xingwang Deng, Ning Wei. Plant COP9 Signalosome subunit 5, CSN5. Plant Sci, 2014, 224:54-61.

4.  Dan Jin, Wei Lu, Shuzhen Ping, Wei Zhang, Jian Chen, Baoqing Dun, Ruiqiang Ma, Zhonglin Zhao, Jiying Sha, Liang Li, Zhirong YangMing ChenMin Lin. Identification of a new gene encoding EPSPS with high glyphosate tolerance from the metagenomic library. Current Microbiology, 2007, 55:350-355.

5. Fan long Wang, Xianbi Li, Yuejie Li, Jing Han, Yang Chen, Jianyan Zeng, Mei Su, Jingxin Zhuo, Hui Ren, Haoru Liu, Lei Hou, Yanhua Fan, Xingying Yan, Shuiqing Song, Juan Zhao, Dan Jin, Mi Zhang, Yan Pei. Arabidopsis P4 ATPase-mediated cell detoxification confers resistance to Fusarium graminearum and Verticillium dahliae. Nat Commun, 2021, 12: 6426

6. Sheng Tong, Maolian Li, Nemat O. Keyhani, Yu Liu, Min Yuan, Dongmei Lin, Dan Jin, Xianbi Li, Yan Pei, Yanhua Fan. Characterization of a fungal competition factor: Production of a conidial cell-wall associated antifungal peptide, PLOS Pathogen, 2020, Doi: 10.1371/journal.ppat.1008518.

7. Yujie Li, Hui Ren, Yutao Zhao, Jiyuan Sun, Yanhua Fan, Dan Jin, Yan Pei. Characterization of three FK506-binding proteins in the entomopathogenic fungus Beauveria bassiana. Journal of Invertebrate Pathology, 2020, 171: 107334.

8. Junyao Wang, Yuge Ma, Yu Liu, Sheng Tong, Shengan Zhu, Dan Jin, Yan Pei, Yanhua Fan. A polyketide synthase, BbpksP, contributes to conidial cell wall structure and UV tolerance in Beauveria bassiana. Journal of Invertebrate Pathology, 2019, 169: 107280.

9. Shaoman Zhang, Cong Li, Yangyang Zhou, Xiaoji Wang, Hong Li, Ziyi Feng, Haodong Chen, Genji Qin, Dan Jin, William Terzaghi, Hongya Gu, Li-Jia Qu, Dingming Kang, Xing Wang Deng, Jigang Li. TANDEM ZINC-FINGER/PLUS3 Is a Key Component of Phytochrome A Signaling. Plant Cell, 2018, 30(4): 835–852.

10. Yonghong Zhou, Lei Hou, Yongjun Zhang,Yanhua Fan, Zhibing Luo, Dan Jin, Qiaosheng Zhou, YuJie Li, You Wang, Yan Pei. Expression and promoter characterization of BbPacC, a pH response transcription factor gene of the entomopathogenic fungus Beauveria bassiana. Microbiology, 2014, 160(Pt 2):353-61.

11. Cheng Liu, Liquan Guo , Suchithra Menon, Dan Jin, Elah Pick, Xue Jun Wang, Xingwang  Deng , Ning Wei. COP9 signalosome subunit Csn8 is involved in maintaining proper duration of the G1 phase. The Journal of Biological Chemistry, 2013, 288(28):20443-52.

12. Jigang Li, Li Yang, Dan Jin, Cynthia D. Nezames, William Terzaghi, Xing Wang Deng. UV-B-induced photomorphogenesis in Arabidopsis. Protein Cell, 2013, 4(7):  485-492.

13. Jincheng MaQun Zhou, Yonghong Zhou, Xinggang Liao, Yongjun Zhang, Dan JinYan Pei. The size and ratio of homologous sequence to non-homologous sequence in gene disruption cassette influences the gene targeting efficiency in Beauveria bassiana, Appl Microbiol Biotechnol,200982:891–898.

14. Xinggang Liao, Yongjun Zhang, Yanhua Fan, Jincheng Ma, Yonghong Zhou, Dan Jin, Yan Pei. An ethanol inducible alc system for regulating gene expression in Beauveria bassiana, World J Microbiol Biotechnol2009, 25:2065-2069.

15. Zhonglin Zhao, Wei Lu, Baoqing Dun, Dan Jin, Shuzhen Ping, Wei Zhang, Ming Chen, Mingqun Xu, Min Lin. Purification of green fluorescent protein using a two-intein system. Applied Microbiology and Biotechnology, 2008, 77(5): 1175-1180.

16. Aimin Liang, Jiying Sha, Wei Lu, Ming Chen, Liang Li, Dan Jin, Yongliang Yan, Jin Wang, Shuzhen Ping, Wei Zhang, Yiding Wang, Min Lin. A single residue mutation of 5-enoylpyruvylshikimate-3-phosphate synthase in Pseudomonas stutzeri enhances resistance to the herbicide glyphosate. Biotechnology Letters, 2008, 30(8):1397-1401.

17. 金丹,陈明,马瑞强,杨志荣,陈建。DNA shuffling技术鉴定草甘膦N-乙酰转移酶抗性相关位点。《中国农业科技导报》,200795):110-114

18. 沙纪莹,金丹,陆伟,张晓喻,张超,李亮,马瑞强,肖磊,王一丁,林敏。极端污染环境草甘膦抗性菌株的分离、鉴定及特性。微生物学报,2008486):824-828

19. 王劲,徐婧,金丹,杜世章。用体外定向进化的方法对EPSPS合酶基因草苷膦抗性机制的研究。四川大学学报,2007441):155-159

20. 顿宝庆,陆伟,张维,平淑珍,王旭静,陈明,徐玉泉,金丹,王劲,赵仲麟,梁爱敏,侯松娜,Ming-Qun Xu,林敏。 荧光假单胞菌G2-EPSP合酶的拆分和intein介导的活性恢复。科学通报,2006512):1479-1481

21. 陆伟,梁爱敏,孟秀萍,顿宝庆,金丹,穆文超,林敏。利用宏基因组文库筛选草甘膦不敏感的5-烯醇式丙酮莽草酰-3-磷酸合酶(EPSPS)基因。高技术通讯,2006年,1612):1284-1288。顿宝庆,陆伟,平淑珍,张维,陈明,徐玉泉,金丹,赵仲麟,林敏。新型高抗草甘膦N-乙酰转移酶基因的分离及其在大肠杆菌中的表达。高技术通讯,2006年,169):943-947

专利申请:

1. 天冬氨酸蛋白酶基因在改良球孢白僵菌菌株中的应用 (专利号:ZL 2021 1 0871353.9)

2. 高抗草甘膦RD EPSP合酶基因及其编码序列(专利号:ZL20070039338.8

3. 草甘膦乙酰转移酶基因及其应用(专利号:ZL200510086626.X

 

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